The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

In the week 13 preview, J.B. Long breaks down the matchup between the Rams defense and versatile Saints running back Alvin ...

The Bills are seemingly getting healthy heading into the matchup, as linebacker Matt Milano and receiver Keon Coleman both ...

Before locking in your Week 13 Fantasy Football lineup, check out who you should start and sit at wide receiver.

Drones will take the air at Highmark Stadium during the Buffalo Bills game on Sunday night against the San Francisco 49ers.

One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

First responders enjoyed a surprise meet & greet with OL Walker Little, a complimentary meal (including the limited-edition ...

The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

The snow may taper off by kickoff, but conditions ahead of the Bills game Sunday night could still make travel difficult.

Week 17 features eight standalone games. And the NFL will have some big decisions to make regarding how to configure the ...

Ready for a battle: The Steelers will face a Cincinnati Bengals team on Sunday that is hungry to get back in the win column ...

But even when most or all of those Niners took the field this year, closing out games has been a glaring weakness for a team expected to compete for the NFC. A loss to Seattle in Week 11 marked the ...