Background Bronchoalveolar lavage (BAL) is essential in determining the efficacy of novel therapies in alpha-1 antitrypsin deficiency (AATD). These require initial proof-of-concept demonstration that ...

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8 Respiratory Medicine Department, University Hospitals Plymouth NHS Trust, Plymouth, UK 9 Department of Respiratory Medicine, Brighton and Sussex University Hospitals NHS Trust, Brighton, UK 10 ...

Atypical radiological manifestation of sarcoidosis presenting with an anterior mediastinal mass ...

Correspondence to Professor Weihong Chen, Department of Occupational and Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, ...

10 Centre Valaisan de Pneumologie et Département de Médecine Interne du Centre Hospitalier du Centre du Valais, Crans-Montana, Switzerland 11 Division of Pulmonary Medicine, University Hospital of ...

Background Asthma and chronic obstructive pulmonary disease (COPD) are the most prevalent respiratory diseases, yet the lack of accessible standardised diagnostics in primary care often lead to ...

Asthma exacerbations are common. They account for a significant morbidity and contribute a disproportionate amount to the cost of asthma management. The optimal strategies for the prevention of asthma ...

Introduction and Objectives Metered Dose Inhalers (MDIs) account for 3% of NHS carbon emissions. In April 2022, NHS England introduced two indicators focussed on reducing avoidable carbon emissions ...

Introduction and Objectives Oral corticosteroids (OCS) are sometimes used to manage exacerbations in patients with chronic obstructive pulmonary disease (COPD). Evidence suggests chronic OCS use is ...

Background A challenging problem arising from cystic fibrosis (CF) newborn screening is the significant number of infants with hypertrypsinaemia (HIRT) with sweat chloride levels in the intermediate ...

1 Department of Respiratory Medicine, Division of Immunology, Infection and Inflammation, University of Glasgow, Glasgow, UK 2 Department of Immunology, Division of Immunology, Infection and ...