San Francisco 49ers wide receiver Jauan Jennings rewards the 49ers' fourth-down call with a 26-yard catch and run.

San Francisco 49ers rookie running back Isaac Guerendo's 15-yard rushing score gives the 49ers their first touchdown of their ...

Leading the way once again was the Bills’ quarterback, who was responsible for three of his team’s five touchdowns. ...

San Francisco 49ers quarterback Brock Purdy is poised to return to action on Sunday night against the Buffalo Bills after ...

San Francisco 49ers star running back Christian McCaffrey departed Sunday night's snow game against the Buffalo Bills early ...

One week after a 38-10 road loss to the Green Bay Packers that stood out as one of their ugliest defeats in years, the San ...

Star quarterback Josh Allen and the Buffalo Bills are back in the playoffs for the sixth straight year and clinched their ...

Josh Allen scored a receiving touchdown on a pass he threw in his latest do-everything performance, and the Buffalo Bills ...

Buffalo Bills star Josh Allen had a career night as he became the first quarterback to record a passing, rushing and ...

The 49ers’ third straight defeat came in 35-10 fashion to the AFC East-clinching Buffalo Bills amid a snowstorm at Highmark ...

Running away with the AFC East: For the fifth consecutive season, the Bills are AFC East champions. This season was ...

Philadelphia Eagles running back Saquan Barkley had another stellar outing in Sunday’s big win over the Baltimore Ravens. The ...