Toll-like receptors (TLRs) and their signalling pathways ... The production of IL-6 and TNF-α is also induced by imiquimod 20. The dsRNA mimic IPH-3102 activates NF-κB signalling and type ...
Schematic of TNF inhibitors and their mode of action. Receptor (i.e. etanercept, lenercept) and antibody based (i.e. infliximab, adalimumab, golimumab) anti-TNF biologics inhibit both solTNF and ...
The discovery of microbial-sensing proteins called Toll-like receptors is transforming our ... result in a messy form of cell death called necrosis, which releases intracellular components into ...
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Researchers decipher new molecular mechanisms related to biological tissue regenerationA new study published in The EMBO Journal opens new perspectives to better understand how the molecular mechanisms involved in regenerative medicine work. The study focuses on tumor necrosis ...
This manuscript presents a valuable minimal model of habituation which is quantified by information theoretic measures. The results here could be of use in interpreting habituation behavior in a range ...
Image Credit: ACROBiosystems CD3 molecules tend to bind to TCR non-covalently to develop a TCR/CD3 receptor complex on the T-cell’s surface. There are four subtypes of CD3 — CD3ε, CD3δ ...
Objective Paraoxonase-1 (PON1) is a high-density lipoprotein (HDL)-associated enzyme, that has been implicated as a biomarker ...
Two common natural nootropics are Bacopa Monnieri, known to support memory and reduce anxiety, and Rhodiola Rosea, reputed ...
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Association between vitamin D supplementation and fatigueThe vitamin modulates the nuclear factor erythroid 2-related factor 2/peroxisome proliferator-activated receptor gamma coactivator 1 ... pro-inflammatory cytokines such as interleukin-2, tumor ...
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A Pit Viper Snake Can 'See' You, Even in the DarkPit vipers also carry venom in twin glands behind their eyes, delivered through movable fangs that can be folded up against ...
Performance enhancing drug abuse and cardiovascular risk in athletes: implications for the clinician
Other growth factors are commonly used in between courses of anabolic agent use and these include human chorionic gonadotropin (HCG) and erythropoietin (EPO) and more recently selective androgen ...
Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.
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