They were totally oblivious to the added TNF. Indeed ... and dephosphorylation events. Death receptors, it was assumed, must signal in a similar fashion. Here came the second major surprise ...

Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.

Toll-like receptors (TLRs) and their signalling pathways have therapeutic ... The production of IL-6 and TNF-α is also induced by imiquimod 20. The dsRNA mimic IPH-3102 activates NF-κB ...

Stanford type A aortic dissection (AD) is a degenerative aortic remodeling disease and carries a high mortality rate. It ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

By inhibiting receptor-ligand interactions in sebaceous glands, antibodies may be able to treat certain skin conditions.

In a recent study published in Nature, researchers examine how sleep impacts inflammation and recovery following a heart ...

Dysregulated neutrophil activation plays a significant role in sepsis. This study shows that the membrane protein CMTM3 is ...

Background and objectives Shufeng Jiedu Capsules (SFJD), a traditional Chinese medicine preparation, are widely used in the ...

Discover how scientists have uncovered the links between inflammatory proteins and endometrial cancer risk, with IL-6 ...

Eli Lilly (LLY) announced results from two, multi-year, Phase 3 studies that showed patients treated with mirikizumab sustained stable, ...