Deebo Samuel revealed why San Francisco quarterback Brock Purdy was upset after Sunday's win over the Tampa Bay Buccaneers.

Cade Otton is showing the rest of the NFL the type of offensive weapon the Tampa Bay Buccaneers always felt he could become.

Tampa Bay Buccaneers Tackle Luke Goedeke was mic'd up for Week 10's Salute to Service game against the San Francisco 49ers. Hear from Luke in this week's edition of Mic'd Up.

San Francisco 49ers quarterback Brock Purdy was announced as NFL Slimetime's "Nickelodeon Valuable Player" for Week 10.

This did not escape two of Mayfield's big media fans, Fox sideline reporter Erin Andrews and studio host Charissa Thompson.

There’s one play from the 49ers' 23-20 win over the Tampa Bay Buccaneers that Nick Bosa would like to have back. The ...

Patrick Mahomes and the Chiefs have squeaked by opponents, but a win is a win, right? Could they really go 17-0? Here's why ...

Having put their best foot forward dealing with a host of injuries, namely to Mike Evans and Chris Godwin, but others in ...

The Seattle Seahawks will visit the San Francisco 49ers in a key game in the NFC West race with both teams trying to catch ...

The San Francisco 49ers have another important division game on Sunday, but they may have to play without two of their biggest stars.

While it’s certainly a positive that the reigning Offensive Player of the Year is back in their lineup, the club now has to ...