One of the most widely used tools for assessing and communicating scientific uncertainty is Grading of Recommendations Assessment, Development, and Evaluation (GRADE), a system for rating the quality ...

Registration of health and medical research is an effective way of improving the transparency and credibility of evidence. Registration involves pre-specifying the research objectives, design, methods ...

Scientific progress requires transparency and openness. The ability to critique, replicate and implement scientific findings depends on the transparency of the study design and methods, and the open ...

In addition to reducing patient harms and wasted resources, efforts to reduce low-value care produce significant climate and population health benefits, but these benefits are typically not elucidated ...

Understanding the causes of deaths and how they can be prevented is critical for improving healthcare outcomes. At a population level, over-reporting or under-reporting of deaths can have a profound ...

Introduction Digital medical devices (e.g., continuous glucose monitors), healthcare apps, and electronic health record tools like patient portals have significantly altered patient self-management ...