San Francisco played without four key players - quarterback Brock Purdy, left tackle Trent Williams, defensive end Nick Bosa ...

NFL Week 13 odds, picks, predictions, TV and streaming information for Sunday Night Football game between the San Francisco ...

The San Francisco 49ers and Buffalo Bills will clash on "Sunday Night Football." Here's how to watch the Week 13 NFL game ...

Here’s how you can watch, stream and listen to the game. Bills vs. 49ers will air on NBC. Mike Tirico will be on play-by-play ...

Getting blown out in Green Bay following another squandered late lead the previous week against Seattle has quickly turned ...

Getting blown out at Green Bay following another squandered late lead the previous week against Seattle has quickly turned ...

Green Bay Packers coach Matt LaFleur hopes the homework he did earlier this month will help his team deal with its compressed ...

San Francisco quarterback Brock Purdy took part in some light throwing after missing his first career game because of an ...

The San Francisco 49ers are on the wrong end of .500, and one NFL exec thinks Kyle Shanahan is due a large portion of the ...

Brandon Allen didn’t get nearly enough help from his more recognizable San Francisco 49ers teammates as the 32-year-old ...

This Sean McDermott stat should give Buffalo Bills fans confidence entering their Week 13 matchup with the San Francisco ...

Ahead of the regular season, the Green Bay Packers' Week 12 matchup with the San Fransisco 49ers was predicted to be a ...