One thing does not change, though. The defending NFC champion 49ers are 5-6 and they need to get on a heater - which will be ...

The Buffalo Bills have the chance to make team history on "Sunday Night Football" against the San Francisco 49ers.

The Bills are seemingly getting healthy heading into the matchup, as linebacker Matt Milano and receiver Keon Coleman both ...

The 49ers are expected to get Brock Purdy back for Sunday's game, and Brian Robinson Jr. (ankle) is set to go for the Commanders.

Running back Christian McCaffrey says the San Francisco 49ers are "hungry" to make a playoff push even with the defending NFC ...

In this episode of Nine & Dime, Los Angeles Rams quarterback Matthew Stafford and wide receiver Cooper Kupp take a trip down ...

Here's everything you need to know for remaining Week 13 NFL games. Which teams will win, who are the X factors, and which ...

Week 17 features eight standalone games. And the NFL will have some big decisions to make regarding how to configure the ...

Plus, rookie quarterback Bo Nix remains focused on the “next game [and] the next opponent” as he continues to earn accolades.

The Buffalo Bills will look to lock up a playoff spot in their Week 13 showdown with the San Francisco 49ers. Here are five ...

The snow may taper off by kickoff, but conditions ahead of the Bills game Sunday night could still make travel difficult.

The Buffalo Bills are in line to accomplish a feat no other NFL club has completed in 15 years – clinch their division after ...