thalidomide which enhances degradation of TNF mRNA, and TACE inhibitors which prevent TACE induced release of solTNF.

The leading Melanoma Companies such as IO Biotech, Moderna Inc., Merck Sharp & Dohme LLC, BioNTech SE, TILT Biotherapeutics ...

Posttranscriptional regulation of TNF mRNA: a paradigm of signal-dependent mRNA utilization and its relevance to pathology.

MSU crystals triggered IL-1β, IL-6 and CXCL1 expression in both pouch exudates and membranes, whereas CCL2 and TNF mRNA were not modulated. The co-injection of MSU crystals and HDL inhibited leucocyte ...

Genascence Corporation ("Genascence"), a clinical-stage biotechnology company revolutionizing the treatment of prevalent ...

Moderna's mRNA vaccine (Spikevax ... 95% CI 0.37-0.90), tumor necrosis factor (TNF) inhibitors (OR 0.55, 95% CI 0.36-0.85), and rituximab (OR 0.27, 95% CI 0.11-0.66), all in comparison with ...

OBJECTIVE To define the pattern of mRNA expression of all human matrix metalloproteinases ... which activates proMMP-2 and proMMP-13 and is involved in tumour necrosis factor α processing. This clear ...

Results Reg4 mRNA and protein were markedly upregulated during arginine ... rReg4 could protect against arginine-induced necrosis of acinar cells both in vivo and in vitro. This protective effect was ...

Results: Interleukin 1β, interleukin 1 receptor II, tumour necrosis factor α, and monocyte inflammatory peptide 2 but not monocyte chemoattractant protein 1 mRNA were detected in the epithelium within ...

Immune regulatory pathways, including TNF and NF-kappa B signaling ... discovered that DR in C. elegans reduces mRNA translation, activates the ISR, and extends the lifespan of the animals.