The finding that their expression is increased following immune-cell activation suggests that ... approaches for therapy based on targeting TNF–TNF receptor (TNFR) interactions: one is to ...

Toll-like receptors (TLRs) and their signalling pathways ... The production of IL-6 and TNF-α is also induced by imiquimod 20. The dsRNA mimic IPH-3102 activates NF-κB signalling and type ...

Tuberculosis and some other granulomatous infections are likely to occur more frequently among patients treated with monoclonal antibodies than among those treated with soluble TNF receptors.

Tumor necrosis factor (TNF)-alpha ... and clinical evidence implicates inflammatory processes and resulting glial activation in the pathogenesis of AD. This small, open-label pilot study suggests ...

Stanford type A aortic dissection (AD) is a degenerative aortic remodeling disease and carries a high mortality rate. It ...

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Dysregulated neutrophil activation plays a significant role in sepsis. This study shows that the membrane protein CMTM3 is ...

Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...

Give the benefit of the doubt to veteran coaches and experienced staff, who are known for their game prep and have navigated the challenges of TNF before. Thursday night games can also be an ...

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Saints cornerback Paulson Adebo broke his femur in the team’s 33-10 loss to the Broncos on Thursday night, in which he was carted off in the first half and taken by ambulance to a New Orleans ...