Tumour Necrosis Factor TNF is crucial for defence but can drive chronic inflammation linked to arthritis and autoimmune diseases when overproduced ...

Several interactions that occur between tumour necrosis factor (TNF ... and TL1A and death receptor 3 (DR3), positively regulate T-cell responses and mediate crosstalk between T cells and other ...

Types of programmed cell death include anoikis, apoptosis, autophagy, necrosis, necroptosis and pyroptosis. After being activated, T lymphocytes must consume fuel for energy and biomaterials to ...

A research team, affiliated with UNIST has developed nanoparticles that effectively treat acute myeloid leukemia (AML), ...

Scientists use cell death, whether by apoptosis or necrosis, to evaluate the toxicity or effectiveness of substances of interest, including potential therapeutic agents. For example, researchers will ...

Necrosis is a form of traumatic cell death that results from acute cellular injury caused by external factors, such as hypoxia in ischemic stroke. However in the penumbra, there are multiple cell ...

Tumor necrosis factor (TNF)-alpha, a proinflammatory cytokine, has been implicated in the pathogenesis of AD. Objective: To investigate the use of a biologic TNF-alpha inhibitor, etanercept was ...

The phase 2 INVINCIBLE-4 clinical trial is currently underway in patients with localized triple-negative breast cancer.