The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out 49ers HC Kyle Shanahan for mishandling late-game situations. Colin Cowherd discusses this criticism and if it’s the biggest issue the 49ers have right now.

Fred Warner, the backbone of the San Francisco 49ers' defense, admitted he's been playing through a fractured ankle, raising questions about the team’s handling of injuries.

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the 49ers haven't looked good over their last three contests.  It wasn't a surprise the 49ers fell to the Green Bay Packers on Sunday with so many key contributors out.

San Francisco 49ers star linebacker Fred Warner revealed that he has been playing through a broken bone in his ankle since September.

One NFL team executive believes the San Francisco 49ers' 5-6 record is partially a product of Kyle Shanahan's coaching. "It's a combination of injuries

Bills' QB Josh Allen is the current favorite for MVP. Expectations aren't something I like to make a habit. However, it's hard not to expect the best from Allen and the Bills this week. Beating the Chiefs the way they did helped them check off that confidence box, and they did it on their 12th straight week of football.

After the Green Bay Packers moved to 8-3, things are looking rosy as far as playoff qualification goes. Here's what to know.

The Green Bay Packers beat the San Francisco 49ers 38-10 at Lambeau Field in Green Bay, Wis. on Sunday. Packers running back Josh Jacobs ran for 106 yards and three touchdowns.

Former Iowa Hawkeyes star George Kittle is in the midst of what has to be the most trying season of his NFL career. Kittle's San Francisco 49ers—who were Super

The Buffalo Bills are set to have a classic snow game matchup against the San Francisco 49ers in Orchard Park.