Buffalo (9-2) brings a six-game winning streak into a matchup with San Francisco (5-6) on Sunday, December 1, 2024 at ...

Buffalo (9-2) brings a six-game winning streak into a matchup with San Francisco (5-6) on Sunday, December 1, 2024 at ...

The #Bills have activated Pro Bowl LB Matt Milano off Injured Reserve and he’ll play on Sunday against the #49ers for the ...

Analyzing Sunday’s San Francisco 49ers at Buffalo Bills odds and lines, with expert NFL picks and predictions.

On Friday, Bills superstar Josh Allen officially announced that he and Hollywood actress Hailee Steinfeld are engaged. Allen ...

The Bills' defense will receive a significant boost for Sunday night's game against the 49ers and the stretch run of the 2024 ...

The table is set for the Bills to clinch a fifth consecutive AFC East title in prime time on WGRZ-TV. Expect them to deliver.

The Bills are activating Matt Milano (biceps) off injured reserve and the linebacker will make his long-awaited return on ...

We can project a good rushing performance again, but when it comes to touchdowns, is it James Cook who scores for the Buffalo ...

The Chiefs escaped with another narrow win and became the first team to clinch a playoff spot in 2024. The Raiders squandered ...

SportsLine's model has simulated San Francisco vs. Buffalo on Sunday Night Football 10,000 times and revealed its SNF picks ...

The San Francisco 49ers were among the Super Bowl favorites heading into the season, but they find themselves below the .500 ...