Objectives To identify whether Mendelian randomisation (MR) studies are appropriately conducted and reported in enough detail for other researchers to accurately replicate and interpret them. Design ...

Correspondence to: Dr Brian S Alper, DynaMed, EBSCO Health, 10 Estes Street, Ipswich, MA 01938, USA; balper{at}ebsco.com Practising evidence-based healthcare (EBHC) is integrating the best research ...

Objectives Alteplase is commonly recommended for acute ischaemic stroke within 4.5 hours after stroke onset. The Third European Cooperative Acute Stroke Study (ECASS III) is the only trial reporting ...

4 Institute of Medical Biometry and Statistics (IMBI), Medical Center – University of Freiburg, Faculty of Medicine, Freiburg, Germany 5 Eye Center, Medical Center, Faculty of Medicine, University of ...

Health inequities have long defined health and the healthcare system in the USA. The clinical and research capacity across the USA is unparalleled, yet compared to other high and even some ...

3 Manitoba Centre for Health Policy, Department of Community Health Sciences, Faculty of Medicine, University of Manitoba, Winnipeg, Manitoba, Canada Correspondence to: Gregory P Marchildon ...

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...

Objectives To investigate the relationship between alcohol consumption and dementia. Design Prospective cohort and case–control analyses combined with linear and non-linear Mendelian randomisation.

This paper is part of a series of methodological guidance from the Cochrane Rapid Reviews Methods Group. Rapid reviews (RR) use modified systematic review methods to accelerate the review process ...

Objectives First, investigate whether a long compared with a short abstract decreases readers’ attention. Second, investigate differences regarding perceptions of informativeness, accuracy, ...

Background The adaptation of clinical practice guidelines (CPGs) is increasingly used to efficiently develop contextualised recommendations for local, regional and national settings. However, ...

A multidisciplinary framework for designing rapidly deployable, scalable and context-specific decarbonisation interventions for clinical care has been developed within the National Health Service, ...