The catalytic hydration of nitriles to amides represents an essential transformation in organic chemistry, offering an atom-economical pathway to synthesise amides that find applications in ...

A pair of copper catalysts can create chiral amides in a new, light-driven process, offering a useful alternative to the standard method for making these staples of medicinal chemistry (Nature 2021, ...

Chemists have been using the Schmidt reaction, which transforms aldehydes and ketones into amides, for nearly 100 years. But the reaction has a downside that prevents it from being widely used: it ...