Hepatocellular carcinoma (HCC) is one of the most fatal malignancies. Epigenetic mechanisms have revealed that noncoding RNAs, such as microRNAs (miRNAs) and circular RNAs (circRNAs), are involved in ...

We identified twelve novel saliva and serum miRNAs and a panel of unique miRNA and mRNA signatures, significantly differentially expressed in saliva and serum of OSCC patients versus HC ...

circRNA, circular RNA; dsRNA, double-stranded RNA; lncRNA, long non-coding RNA; mRNA, messenger RNA; miRNA, microRNA; ncRNA, non-coding RNA; pre-miRNA, precursor ...

The natural RNAi mechanism can be directed by either short interfering RNA (siRNA) or microRNA (miRNA). 1 There are four key steps in the RNAi pathway. When miRNA acts as the guide for RNAi, only a ...

Groundbreaking research uncovers the role of miRNAs in driving cancer while offering innovative diagnostic tools and therapies, including solutions to chemotherapy resistance. Study: miRNA interplay: ...

Professor Hirohide Saito and his research team have developed a new microRNA-responsive hybrid mRNA switch, enabling precise, tissue-specific control of protein expression and pushing the potential of ...

The vector consists of a polyethylene glycolylated liposomal outer coat (providing immune evasion and prolonged circulation), a spindle-shaped nanomotor (resembling a flagellum, facilitating targeted ...

Victor Ambros and Gary Ruvkun were jointly awarded the 2024 Nobel Prize in physiology or medicine for discovering microRNA and its role in post-transcriptional gene regulation, as announced in Sweden ...

Please provide your email address to receive an email when new articles are posted on . The Nobel Assembly at Karolinska Institutet in Sweden announced the honor today. Victor R. Ambros, PhD, and Gary ...