Cell and gene therapies rely on engineered viruses to deliver them to their cellular destinations. While the progress of these types of medicines is evident in a growing number of FDA product ...

A new vector system known as lentiviral vectors can permanently integrate the gene into dividing and non-dividing cells. The capacity of lentiviral vectors to reliably integrate at various genomic ...

Growth and metastasis of malignant tumors requires angiogenesis. Inhibition of tumor-induced angiogenesis may represent an effective cytostatic strategy. We have constructed recombinant ...

Lentiviral vectors were generated by transient transfection of 293T cells according to standard procedures (see the Material and Methods section for details). As anion exchange columns, containing a ...

Acquired from the human immunodeficiency virus (HIV), lentiviral vectors are one of the most practical and commonly used viral vectors. They provide the ability to transduce both non-dividing and ...

Scientists show that envelope proteins derived from the endogenous feline virus RD114 provide a versatile and effective method to pseudotype lentiviral vectors. Therapeutic lentiviral vectors are ...

Viral vectors are critical components of cell and gene therapy products, and they require extensive characterization to ensure their safe and effective use. Capillary electrophoresis is a proven ...

Lentiviral vectors are important gene delivery tools for cell and gene therapies, notably chimeric antigen receptor T-cell (CAR-T cell) therapies which have proven successful in treating a growing ...

Orgenesis announces collaboration agreement with SCTbio to expand POCare sites in the Czech Republic and enhance capabilities for the production of lentivirus vectors Orgenesis’ POCare Platform, ...

GERMANTOWN, Md. and PRAGUE, Czech Republic, May 18, 2023 (GLOBE NEWSWIRE) -- (NASDAQ: ORGS) (“Orgenesis”), a global biotech company working to unlock the full potential of cell and gene therapies (CGT ...