I f your doctor has recommended chimeric antigen receptor (CAR) T-cell immunotherapy for large B-cell lymphoma (LBCL), you’ve likely already tried several standard treatments, and the cancer did not ...

In addition to scalability, another opportunity is presented by clinical feasibility and performance. For example, lymphodepletion conditioning, which is a must for ex vivo-engineered CAR-T cells, is ...

CAR T-cell therapy, which transforms patients’ own immune cells into cancer-fighting warriors, has revolutionized how physicians treat cancer, especially blood cancers. “These patients can be cured ...

T cells are crucial components of our immune system, serving as critical protectors against infection and disease. But there ...

Stem-cell memory T (TSCM) cells are a rare subset of immune cells with the ability to self-renew, persist long term, and ...

The classical paradigm in immunology is that the immune system protects self from non-self. However, there are many cases where the immune system needs to tolerate non-self to avoid complications or ...

Kidney damage is a serious complication affecting individuals with lupus, an autoimmune disease where immune B cells ...