Innate immunity constitutes the body’s first line of defence against invading pathogens. This ancient, evolutionarily conserved system is activated within minutes of encountering foreign agents, ...

Unlike transient innate immune activation, trained immunity is characterized by long-lasting but reversible functional reprogramming of monocytes, macrophages, natural killer (NK) cells, and ...

Scientists discover how innate immunity envelops bacteria. The protein GBP1 is a vital component of our body's natural defense against pathogens. This substance fights against bacteria and parasites ...

We sometimes hear about the benefits of “boosting” our immune system, but what we really want to do is support our immune system on an ongoing basis. People often think of the immune system as ...

Our immune system is divided into two main branches: innate and adaptive. Innate immune cells act as a first line of defense, quickly responding to invaders, while adaptive immune cells take a longer ...

Scientists generally agree that eukaryotes, the domain of life whose cells contain nuclei and that includes almost all multicellular organisms, originated from a process involving the symbiotic union ...

Innate lymphoid cells, which curiously behave like T cells even though they don’t recognize specific antigens, show promise as a potential cancer therapeutic. In the years that followed, other groups ...

Globally, respiratory tract infections remain the leading cause of both morbidity and mortality amongst the population. The burden is further increased by ...

When a transplanted organ arrives, it’s like a controlled burn that risks becoming a wildfire. The body’s innate immune system senses damage signals, like heat shock proteins (HSP70), and sounds the ...

Cancer immunotherapies, including cancer vaccines, harness and amplify the immune system’s natural ability to detect and attack cancer cells. In this illustration, immune T cells (pink) attach to a ...

Ocular infections and related inflammatory disorders are important causes of visual morbidity worldwide and may arise from viral, bacterial, fungal, and ...

People with hard-to-treat asthma often have to use medicines such as systemic steroids that broadly suppress the immune ...