Cancer research increasingly focuses on the tumor immune microenvironment (TIME), which plays a complex role in cancer cell behavior and metastasis. The composition and interactions of immune cells ...

Metabolism reprogramming is one of the hallmarks of cancer, which enables cancer cells to utilize nutrients in a low-nutrient environment and maintain bio-viability. The metabolism reprogramming, as a ...

Before the Columbia study, no one had looked deeply into the microenvironment ... Some of the patients' tumors, for example, were filled with T cells that produce TNF-alpha, which has been ...

In children, cancer probably arises from ... Promoting tumour apoptosis, diminishing necrosis and enhancing acute inflammation in the tumour microenvironment are novel treatment strategies.

Research uncovers how P-stalk ribosomes regulate cytokine responses, driving immune evasion in tumors across multiple cancer ...

These cells migrate into the tumor microenvironment in a process mediated by the chemokine CCL22, and are capable of suppressing antitumor responses. Ovarian tumors are infiltrated by both ...

Researchers combined advanced imaging techniques with a computational method to probe how immune cells interact with each other, revealing that the interactions between immune cells in the vicinity of ...

As well as a chimeric antigen receptor (CAR), ONK adds a tumor necrosis factor (TNF)–related ... overcome hostile conditions within the tumor microenvironment, which may be especially important ...

One major challenge is the microenvironment surrounding the ... eight out of nine of the mice saw tumor necrosis and ...

In the fight against cancer, chimeric antigen receptor (CAR) T cell therapy has achieved notable success in treating blood cancers. However, it has been largely ineffective against solid tumors.