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Distinct signaling pathway identified as key driver for epithelial cancer developmentA distinct signaling pathway called TNF-α drives the transformation of epithelial cells into aggressive tumor cells. During cancer progression, cells activate their own TNF-α program and become ...
The p38 MAPK regulates intracellular signaling pathways in response to environmental stress. Its inhibition blocks the production of inflammation-causing cytokines, such as IL-1β and TNF-α ...
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