thalidomide which enhances degradation of TNF mRNA, and TACE inhibitors which prevent TACE induced release of solTNF.

IFN-α and TNF-α, which drive the generation of inflammatory immune responses. mRNA in the cytoplasm is translated into the respective protein, which in turn is processed into antigenic peptides ...

The phosphorylation reagent with a nitrobenzyl hydrophobic tag allows production of high purity fully chemically synthesized mRNA and transcriptionally synthesized cyclic mRNA. In an era where ...

difficile or C. diff. In animal models, this first mRNA-LNP C. difficile vaccine was found to protect against C. difficile first-time infections and relapsing infections by inducing a robust ...

CureVac and partner GSK are, meanwhile, also developing an mRNA-based flu vaccine, but are a little further back in development, as their shot is in phase 1 testing.

mRNA vaccines have gained widespread attention for their crucial role in fighting the COVID-19 pandemic. Yet, even before the ...

This means adults have a choice in which COVID vaccine they receive: an mRNA vaccine by Moderna or Pfizer, or Novavax, a protein-based vaccine that targets the virus in a more "traditional" way.

The revolutionary messenger ribonucleic acid (mRNA) technology in some Covid vaccines given to millions of people could be fine-tuned for even greater accuracy, UK scientists say. Genetic ...

Get a deeper insight into the potential performance of Moderna (MRNA) for the quarter ended September 2024 by going beyond Wall Street's top -and-bottom-line estimates and examining the estimates ...

Other viruses, including coronaviruses, also distort protein production by disrupting messenger RNA (mRNA) splicing ... CXCL8 ...