These ligand–receptor pairs also mediate ... the level of signalling that each one triggers and whether different TNF–TNFR interactions induce different cellular responses.
Cite this: TNF Signaling Inhibition in the CNS: Implications for Normal Brain Function and Neurodegenerative Disease - Medscape - Oct 17, 2008.
Toll-like receptors (TLRs) and their signalling pathways have therapeutic ... The production of IL-6 and TNF-α is also induced by imiquimod 20. The dsRNA mimic IPH-3102 activates NF-κB ...
Stanford type A aortic dissection (AD) is a degenerative aortic remodeling disease and carries a high mortality rate. It ...
The following is a summary of “Role of baseline soluble tumor necrosis factor receptor 2 as a biomarker in primary ...
Ulcerative colitis (UC) is a chronic gut inflammatory condition affecting the colon in humans. This study uses human samples as well as a mouse model of colitis induced by a chemical, DSS, to ...
The signaling dysfunction ... such as TNF, that magnify the inflammatory disease process. The B-cell inhibitor approved for use in RA works by attaching to a receptor on the B-cell surface and ...
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