THIN-LAYER CHROMATOGRAPHY (TLC) has long been a staple of the organic laboratory, and its silica-on-glass plates are familiar even to undergraduate chemistry majors. But for advanced applications, TLC ...

Although TLC plates can easily be cut with a glass cutter, and plastic and aluminium sheets can be cut with a pair of scissors, care does need to taken to avoid damage to the chromatographic layer. A ...

Before the advent of commercial pre-coated TLC plates, layers of silica gel and of other sorbents (e.g. cellulose or aluminium oxide) had to be prepared in advance of separation procedures. A typical ...

A conditioning process is applied to guarantee consistency from plate to plate, lot to lot, and chemist to chemist. The user can prevent having to retest their sample or risk the compound decomposing ...

Thin-layer chromatography is a tried and true staple of an organic chemistry lab, but it can be of limited use. Compounds with similar properties and polarities often don’t separate, and chemicals ...

Thin layer chromatography is used to analyse mixtures: determine the number, identity, and purity of compounds present in a mixture. This technique can also be used to visualize the progress of a ...