RNA molecules exhibit an astonishing diversity in structure, which is integral to their myriad cellular functions ranging from gene regulation to catalysis. Advances in experimental techniques and ...

Wiring up the brain's trillions of circuit connections is an enormous job performed by a huge crew of molecules. Among the less understood members are circular RNAs, transcripts from DNA that assume a ...

They disable our defenses and hijack the cellular machinery in order to multiply successfully. For example, the herpes ...

Studying a trio of non-coding RNA molecules produced abundantly in bacterial cells, a SLAC/Stanford-led research team discovered extravagant, multistrand complexes made entirely of RNA—structures they ...

Despite being made from a relatively simple set of building blocks, ribonucleic acid (RNA) has a broad array of complex responsibilities. From providing structure to carrying the instructions for ...

A massively parallel reporter assay quantifies the translational consequence of over one million 5’UTR variants.

Apart from carrying the information to encode proteins in, RNA molecules can adopt intricate 2D and 3D structures. Specifically, the same RNA molecule can switch between ON and OFF structures, ...

New research from University of Delaware RNA biologist Mona Batish and colleagues shows circular RNA is favored for transport ...

In a quest to develop new antiviral drugs for COVID-19 and other diseases, a collaboration led by scientists at The Wertheim ...

Recently, demands in RNA manufacturing for long-chain RNAs exceeding 100 nucleotides, such as single guide RNA (sgRNA) for genome editing, have been increasing. Generally, these types of RNA are ...

The field of RNA structure prediction and modeling has undergone substantial transformation in recent years, reflecting a confluence of innovative computational strategies and expanding experimental ...