In neonatal pulmonary hypertension, the pulmonary arteries fail to adapt to extrauterine life and remain thick walled. In a previous study on normal neonatal resistance arteries, perfusion myography ...

Advanced imaging, like 4D-flow CMR, aids in understanding PA remodeling in different PH subtypes, offering non-invasive differentiation. PAH patients exhibit distinct PA flow characteristics, ...

Drugs currently marketed for pulmonary arterial hypertension have been able to extend the lives of patients but have shown limitations in their ability to prevent or reverse the disease. A novel ...

A new molecular imaging technique -- 18F-FAPI PET -- can detect the first signs of tissue remodeling in patients with pulmonary arterial hypertension (PAH), providing physicians with an early marker ...

AUGUSTA, Ga. (July 5, 2016) - Pulmonary hypertension is a highly lethal disease that transforms the thin, flexible vasculature of the lungs into thick, dysfunctional blood vessels that can kill.

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial ...

BOSTON, MA—Denervation of the pulmonary artery (PA) in patients with Group 1 pulmonary arterial hypertension (PAH) led to a significant increase in 6-minute walk test distance as well as positive ...

Pulmonary hypertension, despite advances in treatment, still has a poor prognosis, which is often associated with right heart failure, and for which pulmonary arterial hypertension (PAH) is a severe ...

The first selective inhibitor of protein kinase R- (PKR)-like endoplasmic reticulum kinase (PERK), GSK-2606414, has been shown to attenuate vascular remodeling in pulmonary arterial hypertension (PAH) ...

AliveGen USA Inc. (AliveGen), a clinical-stage biopharmaceutical company, today announced new preclinical data demonstrating that its investigational therapy ALG-801 delivered superior efficacy ...

Scientists at Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago took a major step toward developing a new treatment for pulmonary arterial ...