In prokaryotic cells, transcription (DNA to mRNA) and translation (mRNA to protein) are so closely linked that translation usually begins before transcription is complete. In eukaryotic cells, however ...

They showed that this four-protein machine, which they call 55LCC, binds to DNA and its associated replication complex. Powered by two motor-like enzymes called ATPases, 55LCC appears to unfold the ...

Scientists have discovered that a protein once thought to simply help load a factor necessary for the copying of DNA, actually plays a key role in ensuring fast and reliable replication—an insight ...

The avian influenza virus needs to mutate to cross the species barrier and to infect and replicate within mammalian cells. Scientists have now deciphered the structure of the avian influenza virus's ...

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified. A protein that is involved in determining which enzymes cut or unwind DNA ...

Cell division, a process fundamental to life, still holds surprises. Researchers from the University of Zurich and the ...

Radiation therapy remains one of the most widely deployed weapons in oncology, yet its effectiveness is routinely undermined by a frustrating biological reality: many cancer cells are simply better at ...

Mayo Clinic researchers have identified a protein that acts like a traffic controller for DNA, preventing damage during cell division - a discovery that could lead to new cancer therapies, according ...

At the scale of individual cells, the human body is constantly in motion. Every second, millions of cells divide, particularly in tissues such as the bone marrow, intestine and skin; neurons and heart ...

Every time a cell divides, it must copy its entire genome so that each daughter cell inherits a complete set of DNA. During that process, enzymes known as polymerases race along the DNA to copy its ...