In the present experiments the effects on insulin secretion of theophylline, a methyl xanthine derivative which inhibits cyclic nucleotide phosphodiesterase 6 and increases the intracellular ...
allowing users to mimic physiological insulin secretion to avoid hypoglycaemia around mealtimes as well as overnight. Novo Nordisk as a current market leader offers multiple widely used insulin ...
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Research shows how insulin-triggering nutrients vary from person to person, with implications for personalized nutritiona professor of cellular and physiological sciences at UBC. "Insulin plays a major role in human health, in everything from diabetes, where it is too low, to obesity, weight gain and even some ...
1 When released, GLP-1 activates its receptor, GLP-1R, in the pancreatic islet β cells, provoking a myriad of metabolic changes characterized by insulin secretion and appetite suppression.
2006;55(1):1-12. Glucokinase is required for GSIR in the physiological range of 4-8 mmol/l. Glucokinase is needed for amino acid and fatty acid stimulation of insulin release. Glucokinase permits ...
The physiological response to physical exertion, including a reduction of insulin secretion, is maintained on therapy with glimepiride. [5] The initial dose of glimepiride when commencing therapy ...
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