How memory survives in immune cells works differently than medical scientists previously believed, according to international researchers.

Investigators led by Navdeep Chandel, Ph.D., the David W. Cugell, MD, Professor of Medicine in the Division of Pulmonary and Critical Care, have discovered how the metabolism of mitochondria supports ...

T lymphocytes differentiate from naïve precursors upon antigen encounter into distinct effector and memory subsets. Following priming by antigen-presenting cells in lymphoid tissues, naïve CD4+ and ...

We owe a lot to tissue resident memory T cells (T RM). These specialized immune cells are among the body's first responders to disease. Rather than coursing through the bloodstream-as many T cells ...

Influenza continues to cause major illness each year in the United States, leading to more than 35,000 deaths annually.

Pre-wired ability in ‘resting’ T cells to remember past viral foes discovered, a promising breakthrough for targeted cancer therapies. A team of immunologists at the University of Massachusetts ...