Background: MUC5AC is a secreted mucin aberrantly expressed by colorectal polyps and carcinoma. It has been hypothesized that aberrant expression of MUC5AC in colorectal carcinoma tissues increased ...
Adjuvant mFOLFIRINOX (mFFX) for resected pancreatic cancer (PC): Long term clinical and genomic outcomes. A phase I/II open-label clinical trial of CPI-613 in combination with modified FOLFIRINOX in ...
Pancreatic cancer is one of the most highly lethal tumors. Pancreatic ductal adenocarcinoma (PDA), a major histological subtype of pancreatic cancer, displays local invasion and distant metastasis ...
Identification of novel actionable SNVs via targeted comprehensive genome profiling in patients with gallbladder and cholangiocarcinoma cancer. KC1036, a novel oral multi-kinase inhibitor, in patients ...
Cystic fibrosis (CF) alters the structure of mucus produced in airway passages. In pigs affected by CF, mucus strands (made of MUC5B protein) are more tangled than normal, and the sheets of mucus ...
PASADENA, Calif.--(BUSINESS WIRE)--Arrowhead Pharmaceuticals Inc. (NASDAQ: ARWR) today announced that it has filed an application for clearance to initiate a Phase 1/2a clinical trial of ARO-MUC5AC, ...
Airway mucus consists of various proteins such as long mucins MUC5AC and MUC5B, both of which contribute greatly to the proper gel-like consistency of this most essential bodily fluid. UNC School of ...
A new study shows KRAS-driven lung cancers are also marked by high levels of 'gel-forming mucins,' as seen in some forms of asthma, chronic obstructive pulmonary disease and cystic fibrosis. The study ...
In the present study we have demonstrated the presence of antibodies to MUC5AC epitopes in sera of healthy individuals, patients with polyps and colorectal carcinoma. In the present study, MUC5AC ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results