Loop diuretics are widely used, especially in patients with hypertension or heart failure plus renal dysfunction. Such patients are particularly susceptible to untoward drug effects. It is, therefore, ...

Please provide your email address to receive an email when new articles are posted on . Acute and chronic HF are associated with sodium retention leading to volume overload and edema. Much of the ...

The main operational objective of diuretic therapy in patients who present congestive heart failure and hypertension is to reduce or to suppress excess bodily fluid. Effective diuretic therapy ...

Most accepted pharmacologic treatments for heart failure are supported by evidence from large clinical trials. In contrast, evidence from large, well-controlled clinical trials to guide the use of ...

Semaglutide reduces the need for loop diuretic use and dose, and has positive effects on symptoms, physical limitations, and body weight in patients with heart failure with preserved ejection fraction ...

Diuretics are a class of medications commonly known as "water pills." There are several different classes of diuretics, each of which works differently in the kidneys to help rid the body of extra ...

Finerenone reduced heart failure events and cardiovascular deaths in patients with HFmrEF or HFpEF when used with diuretics. The study found finerenone reduced hypokalemia risk but increased ...