A recent study posted on the bioRxiv* preprint server explored the glycan shield diversity of sarbecoviruses, furthering the knowledge for developing broad-range pan-coronavirus vaccines. Study: The ...
A type of glycan called “N-glycan” is usually extended by the actions of several enzymes (glycosyltransferases). The terminal sugar “sialic acid” increases protein stability in blood. Once B4GALNT3 ...
In this interview, News-Medical talks to a pioneer of glycan imaging, Richard Drake about glycans, their role in maintaining cellular homeostasis, glycopeptide analysis, and method development for ...
Protein structures solved by cryo-electron microscopy (cryo-EM) or X-ray crystallography often miss the sugar molecules known as glycans that cover large swaths of the proteins’ surfaces. The recently ...