Blood cancers such as leukemia are caused by genetic changes in the blood-forming stem cells of the bone marrow. Scientists ...

Understanding how bone marrow produces blood–and how this whole process can fail–is critical to fighting blood cancers and ...

Our body's "blood factory" consists of specialized tissue made up of bone cells, blood vessels, nerves and other cell types.

Model recapitulates key physiological features of native endosteal niches, and could aid in the study of blood formation in both healthy and diseased conditions.

Researchers discovered that chronic inflammation fundamentally remodels the bone marrow, allowing mutated stem cell clones to ...

Researchers from EMBL, the University Medical Center Mainz (UMC Mainz), and the Department of Biomedicine (Basel) have ...

Blood cancers like leukemia often begin with silent changes deep inside the bone marrow, long before a person ever feels sick ...

A method for imaging the production of blood cells in the bones of mice has revealed the organization of cell lineages, both in a steady state and in response to stressors, such as bleeding and ...

Dendritic cells (DCs) are exceptionally potent antigen-presenting cells (APCs) in the human body and are considered the “sentinels” of the immune system. They are essential in establishing, ...

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component of the immune system that produces type 1 interferon cytokines. These cytokines help ...

Lowering blood pressure and cholesterol levels, quitting smoking, managing diabetes: these evidence-backed approaches remain key ways to reduce the risk of cardiovascular disease (SN: 11/9/15). But an ...