What is 2D liquid chromatography? Two-dimensional (2D) liquid chromatography is a powerful tool to separate complex compound mixtures. The principle behind 2D liquid chromatography is that compounds ...

Downstream bioprocessing steps have long been a challenge to drug manufacturers, particularly the chromatography step for purification of monoclonal antibodies (mAbs). The complexity of traditional ...

Dr. Milton Lee, Professor of Chemistry in the Depart­ment of Chemistry and Biochemistry at Brigham Young University, talks to AZoM about the miniaturization of columns in chromatography and what the ...

Although biopharmaceutical manufacturing covers an extensive range, it is essential that each iteration of a unit operation is in compliance with an unyielding set of operational parameters and ...

Case in point: For more than a century, chromatography practitioners have been separating the components of chemical mixtures by using columns packed with various types of particulate matter. Recently ...

Advanced analytics and modeling can be used to predict downstream failures, allowing for corrective action before batches are lost. In the biopharmaceutical industry, quality and consistency are two ...

In chromatography, the components of a mixture are separated. This is made possible because different components interact with the mobile and solid phases differently, thus either being retained on ...

Liquid chromatography (LC) is a chromatographic technique used to separate and analyze mixtures of chemical components in solution, to determine if a specific component is present or absent and, if ...

Over the past five years interest in new and alternative downstream technologies has increased rapidly. This is due, in part, to the well-documented bottlenecks being created by improved upstream ...

Chromatography is an analytical technique that is used to separate mixtures by distributing the components of a mixture between a stationary phase and a mobile phase. Columns are used in various types ...