Oxidative stress induced by 6-OHDA stimulates autophagy flux, which enhances STX17-mediated autolysosome formation, leading to the degradation of autophagosomal contents. However, in response to ...

What is autophagy: A natural cell process that recycles worn-out parts, supports immunity, and helps cells adapt to stress by breaking down and reusing damaged components. Why it matters: When ...

In a recent study published in the journal Neuron, researchers at the University of Cambridge and Newcastle University, UK, examined the relationship between autophagy, aging, and neurodegeneration.

Aging and cancer are deeply intertwined: advancing age is the single largest risk factor for most malignancies, and many of the molecular processes that ...

Illustration of an autophagosome (light blue double-membrane to the right) engulfing cellular material. David S. Goodsell and Daniel Klionsky/RCSB PDB-101, CC BY-SA Don’t let the textbook diagram of a ...

The ability of plants to grow faster and stronger is traced to autophagy, along with key enzymes and proteins such as AFR7, ...

Findings underpin the scientific rationale for Anavex’s targeted autophagy approach with orally administered blarcamesine Convergence of impaired autophagy and synaptic dysfunction across ...