The police activity was on Market Street, between Annie and New Montgomery streets, the Department of Emergency Management said.

A shooting led to a standoff at Palace Hotel in San Francisco Saturday afternoon, according to police. The police department said they responded to the Palace Hotel on New Montgomery Street at around 12:15 p.m. regarding shots being fired.

A standoff is taking place between police and a person barricaded inside a downtown San Francisco building, officials confirmed.

This year marks half a century since the assassination attempt on President Gerald Ford in Downtown San Francisco.

The San Francisco 49ers' defense gets a boost ahead of their matchup against the Indianapolis Colts on "Monday Night Football."

Waymo's self-driving taxis have been in the spotlight for both negative and positive reasons. This week, the automated ride-hailing taxis went viral after a San Francisco woman gave birth inside a Waymo taxi while on her way to the hospital.

California Attorney General Rob Bonta sent a letter to the U.S. Department of Homeland Security shining a light on what he says are dangerous conditions at the

Colts coach Shane Steichen said DT DeForest Buckner will return from a neck injury and play vs the 49ers on Monday Night Football.