Green Bay is the -249 money line favorite (risk $249 to win $100), while San Francisco is the +202 underdog. Before locking in any Packers vs. 49ers picks, you'll want to see the NFL predictions and betting advice from the proven computer simulation model ...

Brock Purdy was a late-week scratch for Sunday’s game between the San Francisco 49ers and Green Bay Packers due to a bad shoulder, moving the spread for that game a full four points from Packers -1.5 to -5.

Coach Matt Eberflus and the Bears submitted the play to the league for review, claiming the Packers broke a rule by making illegal contact with the long snapper before the block. Had a penalty been called on the field, the Bears would have gained 15 yards and a second chance to kick the game-winning field goal.

The NFL reportedly told the Chicago Bears that Cairo Santos' blocked game-winning field-goal attempt was a legal play by the Green Bay Packers.