Hitoyoshi is a city in Kumamoto Prefecture, Japan. The city was founded on February 11, 1942. As of April 2024, the city has an estimated po…Hitoyoshi is a city in Kumamoto Prefecture, Japan. The city was founded on February 11, 1942. As of April 2024, the city has an estimated population of 29,879 and a population density of 141 per km². The total area is 210.55 km².