A few bones (such as the clavicle and the calvarium) develop within a condensed region of fibrous tissue without a cartilaginous intermediate (membrane bone formation).
Intramembranous ossification is a process that forms flat bones such as the skull and the clavicle, through the remodelling of mesenchymal connective tissue. Intramembranous ossification begins in-utero and continues into adolescence.
Bone Development & Growth The terms osteogenesis and ossification are often used synonymously to indicate the process of bone formation. Parts of the skeleton form during the first few weeks after conception. By the end of the eighth week after conception, the skeletal pattern is formed in cartilage and connective tissue membranes and ossification begins. Bone development continues throughout ...