Mixels is set in a fictional planet known as Planet Mixel, where the eponymous creatures live and engage in adventures across diverse lands. Mixels are split into twenty-four tribes based on fantasy elements or city occupations and have individual powers and traits based on these tribes.
Mixels is centered around a world of colorful creatures who can mix and combine with each other leading to hilarious and surprising results. They are comical, mischievous creatures that live in tribes. Each tribe is based around something unique.